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specialized equipment  (Novasina AG)


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    Novasina AG specialized equipment
    Specialized Equipment, supplied by Novasina AG, used in various techniques. Bioz Stars score: 96/100, based on 190 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/specialized+equipment/10__26656_slash_fr__2017__9_ascii40_5_ascii41___117-42-3-9?v=Novasina+AG
    Average 96 stars, based on 190 article reviews
    specialized equipment - by Bioz Stars, 2026-07
    96/100 stars

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    Experimental design. (a) Stimulation sites for transcutaneous vagus nerve stimulation (tVNS) and sham groups. The tVNS group was stimulated at the left cymba conchae (left panel), while the sham group was stimulated at the left earlobe (right panel). (b) Scheme for Experiment 1. Participants lie in an MRI scanner to measure the baseline GABA + concentration in striatum (STR), dorsolateral prefrontal cortex (DLPFC), and sensorimotor cortex (SM). After that, they received either 30 min of tVNS or sham stimulation in a separate room. Following stimulation, GABA + concentration was remeasured in the same region. (c) Scheme for Experiment 2. A 2-min force-controlled task was performed before stimulation (Task 1), 10 min after stimulation onset (Task 2), 20 min after stimulation onset (Task 3), immediately after the end of the stimulation (Task 4), and 12 min after the end of the stimulation (Task 5). (d) Motor task protocol. Each trial consisted of two 60-s blocks and lasted 2 min. Participants were instructed to adjust the pinch force using their right thumb and index finger to quickly and accurately match a randomly moving target line.

    Journal: Frontiers in Human Neuroscience

    Article Title: Transcutaneous vagus nerve stimulation reduces total striatal GABA+ content, increases DLPFC Glu content, and facilitates early-phase motor learning

    doi: 10.3389/fnhum.2026.1731345

    Figure Lengend Snippet: Experimental design. (a) Stimulation sites for transcutaneous vagus nerve stimulation (tVNS) and sham groups. The tVNS group was stimulated at the left cymba conchae (left panel), while the sham group was stimulated at the left earlobe (right panel). (b) Scheme for Experiment 1. Participants lie in an MRI scanner to measure the baseline GABA + concentration in striatum (STR), dorsolateral prefrontal cortex (DLPFC), and sensorimotor cortex (SM). After that, they received either 30 min of tVNS or sham stimulation in a separate room. Following stimulation, GABA + concentration was remeasured in the same region. (c) Scheme for Experiment 2. A 2-min force-controlled task was performed before stimulation (Task 1), 10 min after stimulation onset (Task 2), 20 min after stimulation onset (Task 3), immediately after the end of the stimulation (Task 4), and 12 min after the end of the stimulation (Task 5). (d) Motor task protocol. Each trial consisted of two 60-s blocks and lasted 2 min. Participants were instructed to adjust the pinch force using their right thumb and index finger to quickly and accurately match a randomly moving target line.

    Article Snippet: In both Experiments 1 and 2, the vagus nerve was stimulated noninvasively using a specialized tVNS device (Soterix Medical, Inc., USA).

    Techniques: Concentration Assay

    tVNS reduced total GABA+ concentration in the striatum. STR: Striatum; DLPFC: Dorsolateral prefrontal cortex; SM: Sensorimotor cortex. Striatal GABA+ significantly decreased following tVNS but not sham stimulation (* p = 0.041). No significant changes were observed in the DLPFC or SM. Error bars indicate ±standard deviation.

    Journal: Frontiers in Human Neuroscience

    Article Title: Transcutaneous vagus nerve stimulation reduces total striatal GABA+ content, increases DLPFC Glu content, and facilitates early-phase motor learning

    doi: 10.3389/fnhum.2026.1731345

    Figure Lengend Snippet: tVNS reduced total GABA+ concentration in the striatum. STR: Striatum; DLPFC: Dorsolateral prefrontal cortex; SM: Sensorimotor cortex. Striatal GABA+ significantly decreased following tVNS but not sham stimulation (* p = 0.041). No significant changes were observed in the DLPFC or SM. Error bars indicate ±standard deviation.

    Article Snippet: In both Experiments 1 and 2, the vagus nerve was stimulated noninvasively using a specialized tVNS device (Soterix Medical, Inc., USA).

    Techniques: Concentration Assay, Standard Deviation

    TVNS increased total Glu concentration in the DLPFC. STR: triatum; DLPFC: orsolateral prefrontal cortex; SM: ensorimotor cortex. DLPFC Glu significantly increased following tVNS but not sham stimulation (* p < 0.05). No significant changes were observed in the STR or SM. Error bars indicate the ±standard deviation.

    Journal: Frontiers in Human Neuroscience

    Article Title: Transcutaneous vagus nerve stimulation reduces total striatal GABA+ content, increases DLPFC Glu content, and facilitates early-phase motor learning

    doi: 10.3389/fnhum.2026.1731345

    Figure Lengend Snippet: TVNS increased total Glu concentration in the DLPFC. STR: triatum; DLPFC: orsolateral prefrontal cortex; SM: ensorimotor cortex. DLPFC Glu significantly increased following tVNS but not sham stimulation (* p < 0.05). No significant changes were observed in the STR or SM. Error bars indicate the ±standard deviation.

    Article Snippet: In both Experiments 1 and 2, the vagus nerve was stimulated noninvasively using a specialized tVNS device (Soterix Medical, Inc., USA).

    Techniques: Concentration Assay, Standard Deviation

    tVNS improved force-control motor task performance. Time course of the mean error during the force-control motor task. The red line represents the tVNS group and the blue line represents the sham group. Each task consisted of two blocks. Error values were averaged within each block and corresponding blocks compared between tVNS and sham groups. In block 1 (10 min post-stimulation), the tVNS group showed a significantly lower error value compared with the sham group (* p < 0.05). Error bars indicate the SD.

    Journal: Frontiers in Human Neuroscience

    Article Title: Transcutaneous vagus nerve stimulation reduces total striatal GABA+ content, increases DLPFC Glu content, and facilitates early-phase motor learning

    doi: 10.3389/fnhum.2026.1731345

    Figure Lengend Snippet: tVNS improved force-control motor task performance. Time course of the mean error during the force-control motor task. The red line represents the tVNS group and the blue line represents the sham group. Each task consisted of two blocks. Error values were averaged within each block and corresponding blocks compared between tVNS and sham groups. In block 1 (10 min post-stimulation), the tVNS group showed a significantly lower error value compared with the sham group (* p < 0.05). Error bars indicate the SD.

    Article Snippet: In both Experiments 1 and 2, the vagus nerve was stimulated noninvasively using a specialized tVNS device (Soterix Medical, Inc., USA).

    Techniques: Control, Blocking Assay